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AN INNOVATIVE APPROACH TO STUDY CANINE HIP DYSPLASIA (CHD) IS BEING DEVELOPED AT CIBIO-InBIO AND UTAD

This video highlights the review article “Emerging insights into the genetic basis of canine hip dysplasia”, co-authored by CIBIO-InBIO researcher Catarina Ginja and published in the scientific journal Veterinary Medicine: Research and Reports. In it, Catarina shares some insights about the innovative approach that is currently being developed in collaboration with veterinary researcher Mário Ginja from the University of Trás-os-Montes e Alto Douro (UTAD).

 

Canine hip dysplasia (CHD) is a common inherited polygenic orthopedic condition, whose phenotypic expression is also influenced by environmental factors. This trait leads to a debilitating secondary hip osteoarthritis, with varying degrees of severity. The diagnosis is confirmed radiographically and there is no ideal medical or surgical treatment. Therefore, prevention based on controlled breeding is considered to be the optimal approach.

 

To understand the genetic basis of this disease, molecular studies have been carried out. Nevertheless, the advancements on our state of knowledge about it have been slow. In this context, researchers from CIBIO-InBIO and UTAD’s Department of Veterinary Sciences-CITAB will use whole-genome markers to better understand the genetics behind CHD in Serra da Estrela Mountain dogs. Ultimately, the outcomes of this project will acquaint breeders with the need to take into account genetic information,

 

To access the original article, please see:


Ginja M, Gaspar AR, Ginja C (2015) Emerging insights into the genetic basis of canine hip dysplasia, Veterinary Medicine: Research and Reports, 6: 193-202. DOI: http://dx.doi.org/10.2147/VMRR.S63536

 

Click here to watch the video (Portuguese only)

2015-05-25
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